Angelo: Hey Ian, we’re gonna kill ya! Opa!
- Joel Zwick
- Nia Vardalos (Toula)
- John Corbett (Ian Miller)
- Lainie Kazan (Maria Portokalos)
- Michael Constantine (Gus Portokalos)
- Andrea Martin (Aunt Voula)
- Joey Fatone (Angelo)
- Louis Mandylor (Nick Portokalos)
- Gia Carides (Cousin Nikki)
- Christina Eleusiniotis (Toula as child)
- Marita Zouravlioff (Toula Teenager)
- Gerry Mendicino (Uncle Taki)
- Bess Meisler (Yiayia)
- Jayne Eastwood (Mrs. White)
- Fiona Reid (Harriet Miller)
- Bruce Gray (Rodney Miller)
- Nia Vardalos
- Gary Goetzman
- Tom Hanks
- Rita Wilson